FIG. 10.

Diffusible signals from plasma derived from TBI rats—but not SCI—promote neural stem cell proliferation. No differences in secondary or tertiary neurosphere expansion were noted between cultures treated with plasma derived from SCI and laminectomy-only control animals. Significant increases in the total number of neurospheres per well were observed in cultures treated with TBI plasma compared with craniotomy-only control group. CCI, Controlled cortical impact; SCI, spinal cord injury; TBI, traumatic brain injury.