FIG. 5.

Cervical contusion SCI did not alter the microglia/macrophage response in CVO niches. (A, A’’) Expression of microglia/macrophage marker Iba-1 by BrdU-labeled cells in ME at 28 days after laminectomy. Arrowheads point to an example of a BrdU-labeled cell that is not expressing Iba-1. (A’’’) Higher magnification image showing co-localization of Iba-1 and BrdU in laminectomy tissue. (B, B’’) Expression of Iba-1 by BrdU-labeled cells in ME at 28 days after SCI. (B’’’) Higher magnification image showing co-localization of Iba-1 and BrdU in SCI tissue. (C) Number of BrdU-labeled cells expressing Iba-1 in CVO regions at 4 days and 28 days after laminectomy or SCI. BrdU, bromodeoxyuridine; CVO, circumventricular organs; ME, median eminence; SCI, spinal cord injury. Color image is available online at www.liebertpub.com/neu