FIG. 2.

Treadmill training does not influence motor recovery. (A) Animals were tested weekly starting from 35 dpi in an open field and their motor recovery was scored according to the Basso Mouse Scale (BMS). Spinal cord injury (SCI) mice in the trained and untrained group showed a significant motor deficit (analysis of variance, p < 0.0001), which is not influenced by treadmill training. (B) As animals became accustomed to the treadmill training, the training intensity was adjusted on a daily basis by increasing the treadmill velocity. Training was initiated 42 dpi, which is represented as Day 1 in the graph. Both Sham and SCI mice were trained using similar velocities. Error bars in (B) are mostly too small to be visible.