FIG. 5.

Treadmill training ameliorates spinal cord injury (SCI)-induced thermal hypersensitivity (Hargreaves' test). SCI mice show a decreased response latency to the heat stimulus developing significant thermal hypersensitivity (analysis of variance, p < 0.0001; protected least significant difference [PLSD] ##p < 0.01; ####p < 0.0001, comparing SCI and SCI+T with sham and sham+T animals), which is partially reversed by treadmill training (PLSD) ****p < 0.0001, comparing trained with untrained SCI mice).