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. 2018 Aug 31;15:248. doi: 10.1186/s12974-018-1287-1

Fig. 5.

Fig. 5

Tryptase could upregulate the production of MMP-9 and MMP-2. Mouse brain microvascular endothelial cell were accordingly pretreated with FS at 400 μM for 30 min and then stimulated with tryptase at 1 μg/ml for 24 h. a, b Western blotting analysis of MMP-9 and MMP-2 levels, which were quantified and normalised to their respective GAPDH levels. Each value was then expressed relative to the control, which was set to 1 (n = 3). **P < 0.01 versus the control group. ##P < 0.05 versus the tryptase group. The data are presented as the mean ± S.E.M of at three separate experiments