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. 2018 Aug 29;8(8):e019845. doi: 10.1136/bmjopen-2017-019845

Table 3.

Baseline data on illness and treatment burden (participants)

ICC (95% CI)
Health-related quality of life—EQ5D (n=1546) Mean (SD), range −0.51 to 1.00 0.558 (0.287) 0.033
(0.007 to 0.059)
General health (n=1546) Poor 321 (21%) 0.034
(0.008 to 0.060)
Fair 681 (45%)
Good 429 (28%)
Very good 88 (6%)
Excellent 5 (0.3%)
Bayliss et al 23 Mean count (SD), n, range 1–73 7.5 (3.2), 1543 0.003
(0.000 to 0.014)
Mean illness burden* (SD), n, range 1–26 18.8 (12.4), 1458 0.023
(0.001 to 0.046)
Depression—HADS (n=1512) Normal (0–7) 932 (62%) 0.041
(0.011 to 0.070)
Mild (8–10) 285 (19%)
Moderate (11–14) 211 (14%)
Severe (15–21) 84 (6%)
Anxiety—HADS
(n=1506)
Normal (0–7) 964 (64%) 0.029
(0.005 to 0.053)
Mild (8–10) 246 (16%)
Moderate (11–14) 204 (14%)
Severe (15–21) 92 (6%)
Mean no of medications (self-report) Mean (SD), range 0–34 8.36 (3.94) 0.018
(0.000 to 0.039)
No of medications (n=1396) 0–4 171 (12%) 0.018
(0.000 to 0.039)
5–9 781 (56%)
10–14 350 (25%)
15+ 94 (7%)
Multimorbidity Treatment Burden Questionnaire (n=1524) None (0) 308 (20%) 0.026
(0.003 to 0.049)
Low (<10) 385 (25%)
Medium (10–22) 425 (28%)
High (≥22) 406 (27%)

*Each self-reported health condition is weighted by the extent to which it affects the participant’s life, from 1 (not at all) to 5 (a lot).

HADS, Hospital Anxiety and Depression Scale; ICC, intracluster correlation coefficient.