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15N chemical shift differences, |Δδ(15N)| = |δI – δF|, between the meta-stable intermediate and natively folded VA2-ubiquitin. (A) Color coded on a backbone ribbon structure. Residues for which Δδ(15N) could not be determined are shown in grey. (B) Δδ(15N) as a function of residue number, with negative values depicted as open bars.
