Figure 4.

Schematic representation of the ¹³C label distribution, across the detected metabolites in the mouse brain exposed to ultrasound (US, bottom) and not exposed to US (top), 75 s after the intravenous injection of [1-¹³C]lactate. Each square represents a metabolic pool, with the gray part corresponding to the ¹³C-labeled fraction. The gray arrows represent the ¹³C label flux between the pools. Note that the relative size of the squares or the gray area within each pool is not scaled to the real pool size ratios or the proportion of the ¹³C label.