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. Author manuscript; available in PMC: 2019 Oct 1.
Published in final edited form as: Clin Immunol. 2018 Jun 9;195:139–148. doi: 10.1016/j.clim.2018.06.003

Figure 6. Proinflammatory cytokines and chemokines produced by PBMCs with or without pre-incubated with glucose in response to poly I:C stimulation.

Figure 6

A. PBMCs (1×106) from healthy blood donors were stimulated with poly I:C (20 ug/ml) in the presence of different concentrations of glucose for 24 h. Then, the supernatants from the cultures were measured for cytokines/chemokines using the 22 human cytokine multiplex kits. A representative of four independent experiments is depicted. B. PBMCs (1×106) were pre-incubated with different concentrations of glucose for 48 h, then stimulated with poly I:C (20 ug/ml) for an additional 24 h. Thereafter, the supernatants were measured for cytokines/chemokines using the 22 human cytokine multiplex kits. A representative of four independent experiments is depicted. *: p<0.05; **: p<0.01.