Figure 2.

Dose-response effects of NBOMe compounds and their 2C analogs to inhibit binding of [³H]M100907 at 5-HT_2A receptors in rat brain tissue. Various concentrations of test compounds were incubated with 1 nM [³H]M100907, and assays were terminated using rapid filtration. Non-specific binding was determined in the presence of 10 µM ketanserin. Data are % inhibition of specific binding in the absence of added drug and are expressed as mean ± SEM for N=3 experiments performed in triplicate.