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. Author manuscript; available in PMC: 2019 Jul 15.
Published in final edited form as: Cancer. 2018 May 4;124(14):3025–3036. doi: 10.1002/cncr.31409

Table 1.

Patient Characteristics and Cohort Comparisons

Chemotherapy in ICU
All N (%) Chemotherapy N (%) No Chemotherapy N (%) p-value
Sample Size 362 181 181

Age at Admission, years Median (range) 62 (18-87) 62 (18-86) 62 (19-87) 0.81
Gender Male 230 (63.5) 115 (63.5) 115 (63.5)
Female 132 (36.5) 66 (36.5) 66 (36.5)
MPM II Score Median (range) 42.3 (7.40-94.7) 39.1 (7.40-94.7) 45.6 (8.28-94.0) 0.57
Cancer Type Lymphoma 206 (56.9) 103 (56.9) 103 (56.9)
Leukemia 156 (43.1) 78 (43.1) 78 (43.1)
Primary Admit Diagnosis Bleeding 25 (7.6) 11 (6.2) 14 (9.1)
Cardiac 19 (5.7) 7 (4) 12 (7.8)
Chemotherapy Admin 45 (13.6) 45 (25.4) 0 (0)
Hematologic 4 (1.2) 4 (2.3) 0 (0)
Neurological 9 (2.7) 6 (3.4) 3 (1.9)
Renal 32 (9.7) 23 (13) 9 (5.8)
Respiratory 59 (17.8) 33 (18.6) 26 (16.9)
Sepsis 128 (38.7) 47 (26.6) 81 (52.6)
Other 10 (3) 1 (0.6) 9 (5.8)
Charlson Comorbidity Index Median (range) 6.0 (2.0-13.0) 6.0 (2.0-11.0) 6.0 (2.0-13.0) 0.55
Mechanical Ventilation, on Admit Yes 42 (11.6) 17 (9.4) 25 (13.8) 0.26
No 320 (88.4) 164 (90.6) 156 (86.2)
Mechanical Ventilation, During Stay Yes 137 (37.8) 75 (41.4) 62 (34.3) 0.15
No 225 (62.2) 106 (58.6) 119 (65.7)
Vasopressors, on Admit Yes 41 (11.3) 16 (8.8) 25 (13.8) 0.19
No 321 (88.7) 165 (91.2) 156 (86.2)
Vasopressors, During Stay Yes 123 (34) 59 (32.6) 64 (35.4) 0.63
No 239 (66) 122 (67.4) 117 (64.6)
CRRT/HD Yes 25 (6.9) 17 (9.4) 8 (4.4) 0.11
No 337 (93.1) 164 (90.6) 173 (95.6)
Same Day Hospital/ICU Admit Yes 86 (23.8) 34 (18.8) 52 (28.7) 0.036
No 276 (76.2) 147 (81.2) 129 (71.3)
ICU LOS, days Median (range) 5 (0-47) 6 (1-47) 3 (0-28) <.001
Hospital LOS, days Median (range) 18 (0-126) 22 (2-121) 14 (0-126) 0.024
Hx of Transplant Yes 33 (9.1) 20 (11) 13 (7.2) 0.30
No 329 (90.9) 161 (89) 168 (92.8)
Newly Diagnosed Yes 89 (24.6) 69 (38.1) 20 (11) <.001
No 273 (75.4) 112 (61.9) 161 (89)
Radiation during ICU stay Yes 2 (0.6) 2 (1.1) 0 (0)
No 360 (99.4) 179 (98.9) 181 (100)
# Deaths by ICU Discharge Yes 86 (23.8) 46 (25.4) 40 (22.1)
No 276 (76.2) 135 (74.6) 141 (77.9)
# Deaths by Hospital Discharge Yes 135 (37.3) 76 (42) 59 (32.6)
No 227 (62.7) 105 (58) 122 (67.4)

No comparison was done for gender or cancer type as these were perfectly matched.