Figure 3. Monocyte/lymphocyte ratio is increased in elderly with active TB and decreased in elderly with LTBI, and old age and M.tb infection skew monocytes towards a nonclassical phenotype.
Monocyte/lymphocyte ratio (A) and percent monocytes with nonclassical (CD14dimCD16+) phenotype (B). Boxplots are medians with interquartile ranges. Total subjects for each panel are 91 (A) and 91 (B). Kruskal-Wallis p values were p=0.002 (A) and p=0.003 (B). * p<0.05, ** p<0.01, ***p<0.001 by Dunn’s test, or p value otherwise displayed.