Table 1.
Characteristics of post‐stroke patients with seizure
| Patient characteristics | Percentage (number) | Comparison seizure versus no seizure (P‐ value) | ||
|---|---|---|---|---|
| Overall (n = 722) | Seizure (n = 48) | No seizure (n = 674) | ||
| Age (years); mean (range) | 64.0 (19–97) | 61.2 (35–89) | 64.2 (19–97) | 0.95 |
| Male | 62% (447) | 60% (29) | 62% (418) | 0.12 |
| Hemorrhagic stroke | 26% (191) | 42% (20) | 25% (171) | 0.021 |
| Stroke territories | ||||
| TACS | 7% (49) | 12% (6) | 6% (43) | 0.025 |
| PACS | 40% (285) | 27% (13) | 40% (272) | |
| POCS | 21% (152) | 8% (4) | 22% (148) | |
| LACS | 6% (45) | 10% (5) | 6% (40) | |
| Atherosclerosis | ||||
| Small artery | 33% (175) | 14% (4) | 34% (171) | 0.05 |
| Large artery | 67% (356) | 86% (24) | 66% (332) | |
| Cardioembolic | ||||
| None | 62% (358) | 47% (16) | 63% (342) | 0.13 |
| Moderate | 20% (118) | 24% (8) | 20% (110) | |
| High | 18% (104) | 29% (10) | 17% (94) | |
| APTTa; mean (range) | 26.7 (20.2, 48.3) | 25.6 (22.0, 30.7) | 26.8 (20.2, 48.3) | 0.015 |
| Comorbidities | ||||
| Hypertension | 81% (584) | 77% (37) | 81% (547) | 0.62 |
| Diabetes | 44% (319) | 42% (20) | 44% (299) | 0.82 |
| Hyperlipidemia | 62% (445) | 56% (27) | 62% (418) | 0.52 |
| Ischemic heart disease | 22% (157) | 33% (16) | 21% (141) | 0.07 |
| Atrial fibrillation | 16% (115) | 23% (11) | 16% (104) | 0.25 |
| Management | ||||
| Thrombolysis with alteplase | 6% (41) | 6% (3) | 6% (38) | 1.0 |
| Treatment for raised ICP | 26% (184) | 17% (8) | 26% (176) | 0.20 |
| Statin | 85% (616) | 75% (36) | 86% (580) | 0.056 |
| Fibrate | 6% (44) | 8% (4) | 6% (40) | 0.72 |
| Baclofen | 7% (53) | 12% (6) | 7% (47) | 0.26 |
| SSRI | 18% (131) | 25% (12) | 18% (119) | 0.29 |
| Levodopa | 6% (44) | 21% (10) | 5% (34) | <0.001 |
| Piracetam | 7% (48) | 10% (5) | 6% (43) | 0.44 |
| Sedatives/antipsychotics | 4% (28) | 0% (0) | 4% (28) | 0.29 |
ICP, intracranial pressure; SSRI, selective serotonin reuptake inhibitor.
a
Data unavailable for 104 patients.