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. 2018 Aug 23;12:518. doi: 10.3389/fnins.2018.00518

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Copyright © 2018 Kozin, Barykin, Telegin, Chernov, Adzhubei, Radko, Mitkevich and Makarov.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Characteristic diameter of zinc-induced aggregates for the studied Aβ isoforms. DLS measurements were carried out within 20 min after the addition of zinc to Aβ solutions. Peptide concentration: 25 μM; zinc/peptide molar ratio: 2. Buffer: 10 mM HEPES (pH 7.4), 150 mM NaCl. Mean values and standard deviations for three independent measurements are shown.