Table 3.
Summary of IHC Staining Observed for β-Catenin and E-Cadherin Staining on the Basis of Available Tumor Stage and Nodal Status Information
| Target | Parameter | n | Membranous | Reduced | Absent | P value |
|---|---|---|---|---|---|---|
| β-Catenin | Tumor stage | 144 | 0.0258 | |||
| Tis | 2 | 1 | 1 | |||
| T1 | 26 | 36 | 5 | |||
| T2 | 11 | 37 | 7 | |||
| T3 + T4 | 3 | 12 | 3 | |||
| Nodal status | 133 | 0.0834 | ||||
| N0 | 21 | 43 | 5 | |||
| N1 | 11 | 17 | 5 | |||
| N2 | 3 | 12 | 0 | |||
| N3 | 4 | 12 | 0 | |||
| E-cadherin | Tumor stage | 153 | 0.00541 | |||
| Tis | 3 | 0 | 0 | |||
| T1 | 44 | 26 | 3 | |||
| T2 | 22 | 33 | 3 | |||
| T3 + T4 | 6 | 8 | 5 | |||
| Nodal status | 135 | 0.955 | ||||
| N0 | 33 | 31 | 4 | |||
| N1 | 17 | 16 | 2 | |||
| N2 | 8 | 6 | 1 | |||
| N3 | 8 | 8 | 1 |
IHC, immunohistochemistry; Tis, in situ.