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Controlled release systems for bioactive agents can be effectively achieved with polymeric encapsulation into nano- or microspheres. The images show scanning electron microscopy images of poly(lactic-co-glycolic) acid (PLGA) microspheres at low (A) and high (B) magnifications. As proof of principle, fluorescein (C) green, or hematoporphyrin (D) red, payloads in PLGA microspheres were imaged using a fluorescent microscope.
