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Impaired long bone fracture healing in PTHrP haplo‐insufficient mice compared with wild‐type (WT) mice. PTHrP(+/−) mice exhibited an early transient deficit in callus cartilage a more sustained deficit in callus size and bone content. Day 7 and 14 refer to the time after creation of internally stabilized closed femoral fracture. Data represent means ± SD, n = 6/group. *Significant differences versus wildtype (WT) controls, p < 0.05. Reproduced with permission from Wang et al.39
