Table 1.
CDR amino acid sequences and canonical clusters of InlB-specific VHH
VHH | CDR-1 |
CDR-2 |
CDR-3 |
|||
---|---|---|---|---|---|---|
Sequence | Clustera | Sequence | Cluster | Sequence | Cluster | |
R303 | AASGHTYSTYCMG | 13-6 | RINVGGSSTW | 10-3 | TLHRFCNTWSLGTLNV | 16-1 |
R326 | VTSGRIEGILLVG | 13-5 | SIDRNGNTR | 9-1 | GALSSGVNPWA | 11-1 |
R330 | AASGSSIYTMG | NDb | DISWNGGSTY | 10-2 | NADDLMIDRDY | 11-1 |
R419 | AASGRTYSTYAMG | 13-4 | AINWSGGNTH | 10-2 | AAPKGHTGDHY | 11-1 |
a CDR definitions and structural clusters defined in North et al. (22).
b Not determined; CDR loop could not be classified.