Table 5.

Univariate and multivariate Cox analysis of SigMuc1NW component genes defined at cutpoint for PC recurrence

Factors	Univariate Cox analysis			Multivariate Cox analysis
	HR	95% CI	P‐value	HR	95% CI	P‐value
Agea	1.03	0.99–1.06	0.0981			NSe
GSb	2.19	1.76–2.72	1.49e‐12*	1.71–1.89f	(1.32–1.46)–(2.20‐2.41)f	4.48e‐7*–1.4e‐5*,f
SMarginc	2.25	1.48–3.41	0.000137*			NSe
TumStged	3.68	2.08–6.51	8.19e‐6*	1.62–2.07	(0.85–1.08)‐(3.08–3.96)f	0.0272*,h–0.139f,g
SLCO2A1	2.22	1.27–3.87	0.00499*	1.82	1.04–3.19	0.0369*
SUPV3L1	2.22	1.46–3.38	1.87e‐4*	2.08	1.36–3.19	7.98e‐4*
TATDN2	2.39	1.55–3.70	8.48e‐5*	2.15	1.37–3.37	8.35e‐4*
MGAT4B	2.81	1.83–4.32	2.61e‐6*	1.77	1.23–2.78	0.0128*
VAV2	2.56	1.69–3.89	9.94e‐6*	1.93	1.26–2.95	0.0024*
SLC25A33	2.34	1.13–4.84	0.0218*	2.25	1.08–4.67	0.0297*
ASNS	2.87	1.68–4.90	1.09e‐4*	1.91	1.09–3.36	0.0239*
OIP5	3.46	2.24–5.36	2.64e‐8*	1.94	1.20–3.12	0.00638*

^aAge at diagnosis.

^bRadical prostatectomy Gleason score.

^cSurgical margin.

^dTumor stages (0 for ≤ T2; 1 for T3 and T4).

^eNot significant.

^fRange of HR, 95% CI, and P‐values resulted from multivariate Cox analysis with the individual genes.

^gThe P‐values for SLCO2A1 (P = 0.0749), MGAT4B (P = 0.0891), ASNS (P = 0.0917), and OIP5 (P = 0.139).

^hThe P‐values for SUPV3L1 (P = 0.0431*), TATDN2 (P = 0.0272*), VAV2 (P = 0.0364*), and SLC25A33 (P = 0.0334*).

HR, hazard ratio; CI, confidence interval.