Figure 1.

Elastin‐derived peptides promote MDA‐MB‐231 cancer cell invasiveness. Cells were incubated for 6 h in the presence or absence of κE (50 μg·mL⁻¹) in a modified Boyden chamber in order to assess their invasiveness. Cells were placed in the upper compartment of the system in the presence of the agonist while the lower compartment received only culture medium supplemented with 10% serum. Cells having invaded the Matrigel separating the two compartments and being present on its lower surface were counted after 6 h. (A) Invasiveness expressed as the percentage of the control, here MDA‐MB‐231 cells in the absence of κE. (B) Representative images of violet crystal‐stained invasive cells. ***P < 0.001 (n = 13).