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hAECs switched proinflammatory status into prohealing status of diabetic wounds. Expression levels of IL-6, IL-1β, TNF-α, VEGF, TGF-β1, and IGF-1 in day 10 diabetic wounds were detected by ELISA, showing reduced levels of proinflammatory cytokines and increased expression levels of prohealing cytokines in the hAEC group. Data was shown as means ± SD; n = 6; ∗∗∗P < 0.001.
