Figure 1.

Recombination outcomes of DSB repair pathways during meiosis. DSB resection and strand invasion leads to D‐loop formation. Dissolution of the D‐loop results in non‐crossovers by SDSA mechanism. Protection of D‐loops from disassembly by the ZMM proteins allow double Holliday junction formation that is acted on by Mlh1‐Mlh3 and Exo1 to form the class I crossovers. Alternatively the joint molecules, may also be processed by the structure selective nucleases Mms4‐Mus81, Slx1‐Slx4 and Yen1 to form the class II crossovers and non‐crossovers.