Table 1.

Characteristics of included studies

Reference,author, year	Population, no. of participants, age, site/lesion type	Intervention	Outcomes	Lengthof follow‐up	Result	Effect estimate
Duffy et al11 2006	184 patients with head and neck cancer, mean age 57 y, 84% men, 90% white	Tailored smoking, alcohol, and depression intervention comprising of CBT and pharmacologic management.	Self‐reported smoking cessation rates. Self‐reported problem drinking rates.	6 mo	Smoking: 47% cessation in intervention compared to 31% cessation in control. Alcohol: 32% improved problem drinking in intervention compared to 30% in control	Smoking: P = .048 Alcohol: P = .853
Ghosh et al22 2016	14 participants either undergoing treatment for or observation of premalignant lesions or who had received treatment for head and neck cancer >5 y previously. Mean age 60 y.	Financial incentive for smoking cessation	Self‐reported cessation confirmed by exhaled carbon monoxide at 30 d and self‐reported cessation confirmed by a negative urine cotinine assay at 3 mo and 6 mo	6 mo	33.3% cessation in intervention group compared to 0% in control group	N/A due to small sample size
Gritz et al23 1993	186 participants undergoing treatment for cancers of the oral cavity (54.9%), pharynx (6%), and larynx (39.1%). Mean age 58.5 y, 73.7% men, 72.6% white	A physician and dentist‐delivered smoking cessation intervention involving an initial advice session followed by 6 “booster sessions”	Self‐reported cessation confirmed by urine cotinine validation	12 mo	At 6 mo: 64.3% cessation rate in intervention compared to 71% in control. At 12 mo: 63.8% cessation rate in intervention compared to 76.8% in control.	P values not reported but the authors state no significant difference between the groups

Abbreviations: CBT, cognitive behavioral therapy; N/A, not available.