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Pictorial representation of Plasmodium DBL domain interaction with 7 transmembrane DARC on human erythrocytes. The DBLs are part of Plasmodium-encoded membrane proteins called erythrocyte-binding proteins (EBPs) that drive receptor recognition between merozoites (green) and RBCs (red). The DARC extracellular domain of residues 1–60 contains two key tyrosyl residues at positions of 30 and 41 that are post-translationally sulfated—and are marked in red dots.
