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. 2018 Jul 10;19(16):1758–1765. doi: 10.1002/cbic.201800229

Scheme 2.

Scheme 2

Synthesis of N3‐Cy5‐COOH. a) N‐(3‐Bromopropyl)phthalimide in p‐dichlorobenzene; b) MeNH2 in EtOH/H2O; c) Imidazole‐1‐sulfonyl azideHCl, NMM, CuSO4 (cat.), MeCN/H2O.