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Erythroid Differentiation of Edited and Unedited Wild-Type Cells
(A) Indel percentage 2 days after transfection and on day 20 of erythroid differentiation. (B) Growth of untransfected (untr), exon 2-ZFN-, and enhancer-ZFN-transfected erythroid cells during erythroid differentiation. (C) Cytospin preparations stained with H&E from different time points of erythroid differentiation. (D) Percentage of nucleated over enucleated cells at the endpoint of the culture.
