Fig. 7.

Therapeutic triangle (TT) definition (yellow) between mammillothalamic tracts STN/SNr and red nucleus, respectively. Definition of three stimulation levels for the determination of optimal EC position (A-C). D, sub-parcellation of the TT. E, EC of responders (yellow) are clearly located inside the TT (projection of EC in level 2, only for visualization purposes). A therapeutic effect is likely due to white matter modulation and not due to an inadvertent stimulation of grey matter structures (nuclei) in the proximity. However, this is not clearly defined by a certain position within the triangle but only by the DTI-FT rendition of the slMFB. For details and statistics see text.