Figure 2.

Three-layered structure of Coinami. Root authority issues certificates to research centers, which enables them to distribute HTS jobs to miners. When an HTS job is processed and uploaded successfully, the miner is rewarded with a coinbase transaction that is signed by the subauthority. Before issuing the reward, the subauthority checks whether the alignments are correct using the map location, reference segment, and the string edit fields in the BAM record (i.e., CIGAR and MD); therefore, the generation of the BAM file serves as proof-of-work. These transactions are included in the underlying blockchain. This way, every reward, every transaction is made public so that anyone can inspect the system for a suspicious activity. In this scheme, root authority must be trusted by all parties.