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. 2018 Sep 1;32(17-18):1252–1265. doi: 10.1101/gad.312173.118

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© 2018 Bruzzone et al.; Published by Cold Spring Harbor Laboratory Press

This article is distributed exclusively by Cold Spring Harbor Laboratory Press for the first six months after the full-issue publication date (see http://genesdev.cshlp.org/site/misc/terms.xhtml). After six months, it is available under a Creative Commons License (Attribution-NonCommercial 4.0 International), as described at http://creativecommons.org/licenses/by-nc/4.0/.

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Figure 5. — (A) Heat map representing the result of a k-means clustering analysis on the change in RNAPII occupancy measured in Esa1, Gcn5, Tra1, and Med17 nuclear-depleted cells. (B) Box plots showing the transcription rate measured by nascent elongating transcript sequencing (NET-seq) (Churchman and Weissman 2011) for the genes in the five clusters described in A. (C,D) Bar plots showing the number of Ribi genes (C) and RPGs (D) in each of the five clusters. (E) Box plot showing TBP promoter occupancy for the genes in the five clusters (Kubik et al. 2018). (F) Bar plots showing the percentage of genes having a well-defined TATA box in their promoter (green) and significant TAF1 binding measured by ChIP (purple) as reported in Rhee and Pugh (2012) for each of the five clusters.