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. 2018 Aug 15;3(8):9210–9219. doi: 10.1021/acsomega.8b00949

Figure 7.

Figure 7

In vitro cytotoxicity of drug formulations in MDA-MB-231 breast cancer cells and A-549 lung cancer cells. (A) Cell viability of MDA-MB-231 and A-549 cells after being exposed to various doses of different drug formulations. (B) RIA of cell percent survival under various doses of different drugs. (C,D) IC50 (half maximal inhibitory concentration) and CI50 of different drug formulations exposed to MDA-MB-231 and A-549 cells. (E,F) IC50 and CI50 (between silybin and DOX–PTX) of dual-drug- and triple-drug-loaded Ch-MLNPs when exposed to MDA-MB-231 and A-549 cells. Comparison among groups was conducted by one-way ANOVA followed by Tukey’s HSD analysis, *p < 0.05, **p < 0.01, ***p < 0.001.