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. 2018 Mar 9;57(15):2251–2257. doi: 10.2169/internalmedicine.0387-17

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Copyright © 2018 by The Japanese Society of Internal Medicine

The Internal Medicine is an Open Access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).

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Figure 2. — Histopathological evaluation of the pleura and pleural effusion. A pleural biopsy showed the presence of dense lymphoplasmacytic infiltrate [(A): Hematoxylin and Eosin (H&E) staining, ×40; (B): H&E staining, ×100]. Immunohistochemically, many IgG4-poisitive plasma cells are identified (IgG4-positive plasma cells >50/HPF, IgG4⁺/IgG⁺cell ration <40%). [(C): immunohistochemical staining for IgG, ×400; (D): immunohistochemical staining for IgG4, ×400]. (E) Ziehl-Neelsen staining identified no acid-fast bacteria.