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. 2018 Sep 3;8:13164. doi: 10.1038/s41598-018-30702-4

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Clusters of altered transcription factor expression and motif activities in SMC exposed to FGF2 or IL-1β. Clusters of altered TF expression in response to (A) FGF2 or (B) IL-1β. Clustering of motif activities in response to (C) FGF2 or (D) IL-1β. Numbers in parentheses denote the number of TFs or motifs within the cluster.