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. 2018 Sep 3;4:18. doi: 10.1038/s41522-018-0059-0

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — Drivers of changes in fecal microbiota composition at the genus level. Bar plot depicting the relative abundance of the 10 most abundant genera in all samples. Samples are divided per cage (A, B, C, D, F, G, I, J, K, L, N, and Q) and the four respective phenotype–genotype combinations (DSS.MMP-9^-/-, DSS.WT, control.MMP-9^-/-, and control.WT). The color intensities of the bars represent the disease activity index (DAI) with brighter colors indicating higher inflammatory burden. Each bar of the histogram represents the cumulative relative abundance of all samples within one group and the line within each bar indicates the separation of each sample within the group. If no line is observed within the bar, only one sample was available