Table 1.
Summary of muscimol injections performed in the SC
| Expt # | Saccade latency asymmetry (ms) | Δ Detection rate asymmetry (%) | Scotoma area (deg2) | Stimulus overlap with scotoma (%) | Distance from stimulus center to scotoma center (deg) | Center of scotoma (x, y deg) | Injection volume (μl) | Subject ID |
|---|---|---|---|---|---|---|---|---|
| 1 | 22.7 | 12.8 | 19 | 0 | 5.3 | 5.4, 2.6 | 0.3 | M |
| 2 | 67 | 22.1 | 158.4 | 79.6 | 2.3 | 10.4, 2.3 | 0.4 | M |
| 3 | 44.4 | 8.9 | 221.5 | 71.5 | 4.1 | 9.0, 0.1 | 0.3 | M |
| 4 | 75.5 | 30.1 | 221 | 84.3 | 5 | 6.5, 0.9 | 0.4 | M |
| 5 | −6.9 | −1.9 | 11 | 3 | 4 | 10.3, −2.4 | 0.5 | M |
| 6 | 6.1 | 9.1 | 81.5 | 0 | 9.2 | 12.0, 5.0 | 0.4 | M |
| 7 | 17.8 | 0 | 15.5 | 4.4 | 4.5 | 9.0, 0.5 | 0.4 | M |
| 8 | 52.2 | 21.8 | 200.7 | 70.9 | 7.3 | 14.1, 1.1 | 0.5 | M |
| 9 | 53.1 | 10.8 | 114.8 | 59.1 | 6.6 | 13.0, 0.4 | 0.5 | M |
| 10 | 28.3 | 16.2 | 165 | 34.8 | 2.7 | 10.7, 0.0 | 0.4 | M |
| 11 | 46.6 | 23.8 | 101.8 | 62.2 | 4.1 | 13.0, −1.4 | 0.4 | M |
| 12 | 59.8 | 10.2 | 46.5 | 36 | 5.3 | 13.9, 0.2 | 0.5 | M |
| 13 | 13.2 | 2 | 49.3 | 1.7 | 6.3 | 12.9, −1.3 | 0.5 | M |
| 14 | 59.2 | −1.7 | 293.8 | 96.6 | 3.7 | 13.5, 1.1 | 0.5 | M |
| 15 | 72.1 | 33.7 | 272.8 | 75.9 | 7 | 13.5, 2.5 | 0.5 | M |
| 16 | 70.7 | 27 | 237.3 | 94.8 | 4.6 | 13.4, 0.0 | 0.5 | M |
| 17 | 22 | −4.2 | 17.3 | 8 | 12.7 | 20.1, 3.7 | 0.5 | M |
| 18 | 4.4 | −2.7 | 14.2 | 5.6 | 4.1 | 10.8, 2.8 | 0.5 | M |
| 19 | 112.7 | 38.7 | 96.3 | 70.8 | 10.7 | 18.0, 4.7 | 0.4 | S |
| 20 | 66.5 | 52.2 | 77.5 | 11.5 | 3.5 | 6.25, 3.0 | 0.3 | S |
| 21 | 83.1 | 35.2 | 55 | 26.5 | 4 | 11.3, 3.3 | 0.4 | S |
| 22 | 59.6 | 35.2 | 178 | 54 | 2.2 | 9.5, 2.8 | 0.3 | S |
| 23 | 55.8 | 18.8 | 201 | 63.3 | 4.1 | 10.9, 5.1 | 0.3 | S |
| 24 | 1.7 | 7.9 | 23.1 | 12.2 | 4.5 | 11.3, −0.3 | 0.4 | S |
| 25 | 49.2 | 34.9 | 111.3 | 32.9 | 1.8 | 6.8, 2.1 | 0.4 | S |
| 26 | 0.1 | 0.2 | 21.1 | 8.8 | 3.2 | 5.6, −0.1 | 0.4 | S |
| 27 | 22.3 | 16 | 25 | 0 | 12.6 | 21.5, 1.7 | 0.4 | S |
| 28 | 40 | 17.2 | 142 | 44.2 | 5.2 | 7.5, 8.1 | 0.3 | S |
| 29 | 33.3 | 15.8 | 115 | 63 | 4.8 | 13.0, 0.6 | 0.4 | S |
| 30 | 32.3 | 19.9 | 100.5 | 45.3 | 6.7 | 4.1, −3.1 | 0.3 | S |
| 31 | 53.6 | 19.8 | 176.8 | 82.1 | 3.1 | 8.8, −1.5 | 0.4 | S |
| 32 | 36.1 | 15.8 | 121 | 39.9 | 1.7 | 7.6, 2.7 | 0.5 | S |
| 33 | 75 | 16.2 | 67.8 | 77.9 | 2 | 10.2, 2.5 | 0.5 | S |
| 34 | 115 | 21.4 | 232.1 | 65.5 | 7.6 | 16.2, −0.4 | 0.5 | S |
| 35 | 50 | 20.1 | 189.4 | 41.2 | 7.7 | 5.6, −5.4 | 0.4 | S |
| 36 | 100 | 28.7 | 95.5 | 52.2 | 8.6 | 14.9, 6.3 | 0.5 | S |
| 37 | 92.5 | 26.4 | 195.2 | 65.3 | 9.1 | 2.6, −6.0 | 0.5 | S |
| 38 | 110 | 29.2 | 163.9 | 69.2 | 2 | 9.8, 1.3 | 0.5 | S |
| 39 | 110 | 25.2 | 175.8 | 88.7 | 5.2 | 12.5, −0.8 | 0.5 | S |
| 40 | 122.5 | 25.4 | 210 | 91.2 | 6.8 | 3.0, 6.1 | 0.5 | S |
| 41 | 31.3 | 36.2 | 81.2 | 88.5 | 1.2 | 8.7, 2.2 | 0.4 | S |
| 42 | 74.8 | 25 | 74.7 | 90.7 | 2.3 | 5.7, 0.6 | 0.5 | S |
| 43 | 28.5 | 31 | 130.3 | 23.3 | 7.8 | 10.5, −5.9 | 0.4 | S |
| 44 | 50.3 | 29.8 | 166.6 | 44.5 | 4.2 | 5.7, 5.0 | 0.5 | S |
| 45 | 102.8 | 36.2 | 140.3 | 65.5 | 9.3 | 17.0, 3.0 | 0.5 | S |
| 46 | 60.4 | 22.1 | 110.5 | 72.8 | 2.2 | 5.6, 1.3 | 0.5 | S |
Experiments are ordered chronologically. Saccade latency asymmetry and Δ detection rate asymmetry are the same values plotted in Figs. 2 and 3. Scotoma area was defined by the areal extent of visual saccade end points with significant increases in latency in each experiment (not fitted or smoothed) and depended on a variety of factors including eccentricity and injection volume; in some cases, the area may be underestimated due to the limited size of our visual display. The stimulus overlap with scotoma was quantified as the percentage of the total stimulus-patch area (on the affected side) that fell within the scotoma. The center of the scotoma was defined as the centroid of the visual saccade end points with significant increases in latency. See also Supplementary Figure 2 for histograms comparing values between SC and FEF