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. 2018 Sep 3;8:13121. doi: 10.1038/s41598-018-31064-7

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Shannon Entropy (a) and Mutual Information (b) of run_171108 reads belonging to clusters of increasing size. Each number on the X axis is the number of successive mapping coordinates in which reads share the same UMI. Cluster size = 1 represents reads mapping to only one location. Box plot hinges represent the first and third quartiles. Whiskers extend no more than 1.5 times the inter-quartile range.