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. 2018 Aug 28;9:1965. doi: 10.3389/fimmu.2018.01965

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Copyright © 2018 Pang, Song, Lu, Zhang, Zheng, Jiang and Zheng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The primary infection of northern pig-tailed macaques with HIV-1_NL4−R3A and stHIV-1sv. 4 NPMs were infected with HIV-1_NL4−R3A and stHIV-1sv, respectively. (A) Plasma viral load, (B) B cell counts, (C) CD4+ T cell counts, (D) CD8+ T cell counts, (E) the ratio of CD4+ to CD8+ T cells in peripheral blood in the primary infection of 28 weeks were measured. P-value differences between HIV-1_NL4−R3A and stHIV-1sv infected groups were calculated by two-way analysis of variance.