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. 2018 Aug 28;9:490. doi: 10.3389/fendo.2018.00490

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Copyright © 2018 Abu Eid, Hackl, Kaplanian, Winter, Kaltenecker, Moriggl, Luger, Scherer and Fürnsinn.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Blood glucose curves during the insulin tolerance test given as absolute concentrations (A) or as relative (%) changes vs. the starting value (B) in four groups of mice after 3 months under different conditions: free access to chow diet (Chow ad lib; n = 8); free access to high fat diet (HFD ad lib; n = 8); free access to HFD under hypoxia (HDF ad lib + Hypoxia; n = 12); restricted access to HFD, weight-matched with the hypoxia-exposed group (HFD restricted; n = 12). Means ± SEM; AOC, area over the glucose curve; p < 0.05 by Student's t-test: bar graphs, ^†vs. Chow ad lib, ^‡vs. HFD ad lib, ^§vs. HFD restricted.