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. 2018 Aug 28;10:250. doi: 10.3389/fnagi.2018.00250

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Copyright © 2018 Petrasek, Vojtechova, Lobellova, Popelikova, Janikova, Brozka, Houdek, Sladek, Sumova, Kristofikova, Vales and Stuchlík.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Morris water maze - hidden platform task. In the hidden platform version of the MWM, McGill rats exhibited longer latencies than their control counterparts (effect of group, p < 0.0001, left panel). The performance of both groups improved with subsequent trials (effect of trial, p < 0.0001), with no interaction between the factors. Thigmotaxis (middle panel) was again higher in the McGill group (p = 0.0001), but in both groups tended to decrease with subsequent trials (p = 0.0014). Savings (a measure of improvement between the first and the second trial within a day) were not significantly different, with a trend toward lower performance of the McGill group when the delay was longer (p < 0.1). *p < 0.05.