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(A) Reduced expression of the LC3A-1 protein in the supernatant of T98 and U87 cell lines, following transfection with specific vs. random non-coding siRNAs. (B, C) Growth kinetics of the wild type and shLC3A transfected T98 (B) and U87 cell lines (C) following subcutaneous implantation in athymic mice. (D) A typical image of a U87 implanted tumor in an athymic mice showing different size of the wild type and shLC3A implanted tumors, 12 days after irradiation.