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. 2018 Aug 17;12:259. doi: 10.3389/fncel.2018.00259

Figure 6.

Figure 6

The regulatory role of Gli3 and miR-7 in neuronal migration in E15.5 cortices. (A,B) Absence of Gli3 facilitated more Tbr1+ marked neurons to migrate into the upper-bins (bin10) in the midline region, while double-lose of miR-7 and Gli3 corrected the migratory process. (C,D) No significant alteration of migratory process was detected in the bin10 in the lateral region in EG and EGS cortices. The markers BrdU, Tbr1 and DAPI stained for proliferative NPs, newborn neurons and all cells, respectively. Values represent mean ± SEM. n > 9. **P < 0.01; ***P < 0.001; ns, not significant. One-way ANOVA with post hoc test was used. Scale bar = 50 μm.