Figure 8.
Proteins regulated as a consequence of GFPT1 depletion in 3 months old intercostal muscles. (A) STRING analyses demonstrating the spectrum of affected proteins. Proteins that show upregulation (green) and downregulation (red) are shown. (B) Immunoblot studies show upregulation of glypican-1 and MuSK proteins in Gfpt1tm1d/tm1d mice. Quantitative analysis showing the relative expression levels of glypican-1 (C) (n = 3), and MuSK (D) (n = 2) normalized to their corresponding α-actinin loading controls.