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Mutant SEC23B p.V594G protein localizes to all nucleolar subcompartments in the presence of ER stress. Confocal microscopy images of Nthy-SEC23B-V594G cells stained with subnucleolar proteins after ER stress treatments (0.1 μg/ml Tunicamycin, day 7). Images were taken using a TCS SP8 confocal microscope (Leica). GC, granular component; DFC, dense fibrillar component; FC, fibrillar center. Blue, DAPI; green, SEC23B-EGFP; red, nucleolar subcompartment. Scale bars, 25 μm.
