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. 2018 Aug 10;19(8):2356. doi: 10.3390/ijms19082356

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Lipidomic perturbations of OMVs isolated from polymyxin-susceptible and -resistant K. pneumoniae isolates. Fold-change of lipids relative to the untreated control cells, in OMVs of the polymyxin-susceptible (i) and -resistant (ii) strains of paired K. pneumoniae isolates in response to polymyxin B treatment (2 mg/L). (A) K. pneumoniae ATCC 700721. (B) K. pneumoniae BM3 and (C) K. pneumoniae FADDI-KP069. GPLs = glycerophospholipids; FA = fatty acids; GL = glycerolipids; SP = sphingolipids.