. 2018 Aug 16;19(8):2426. doi: 10.3390/ijms19082426

Table 1.

Parasitologic and antibody data for vaccinated and control mice challenged with 34 ± 1 Schistosoma japonicum cercariae.

Group	Immunoglobulin		Number Adult Worms Mean ± S.E.	Mean Length of Adult Worms (mm) Mean ± S.E. % Reduction (p Value)	Liver Eggs/g Mean ± S.E. % Reduction (p Value)	Liver Granuloma Density (%) Mean ± S.E. % Reduction (p Value)	Intestinal eggs/g Mean ± S.E. % Reduction (p Value)	Maturity of Intestinal Eggs in Stage V (%) Mean ± S.E. % Decrease (p Value)					Faecal Eggs/g/F Mean ± S.E. % Reduction (p Value)
Group	Before Challenge	Before Perfusion	Number Adult Worms Mean ± S.E.		Liver Eggs/g Mean ± S.E. % Reduction (p Value)		Intestinal eggs/g Mean ± S.E. % Reduction (p Value)	Stage I	Stage II	Stage III	Stage IV	Stage V	Faecal Eggs/g/F Mean ± S.E. % Reduction (p Value)
Control	IgG, IgG1, IgG2a, IgG2c. and IgG3 1:50	-	(F) 5.9 ± 0.7	(F) 10.4 ± 0.2	41,886 ± 6001	30 ± 3.9	64,483 ± 9998	3.4 ± 1.8	15.6 ± 3	27.7 ± 2	31.6 ± 2	21.6 ± 2	1398 ± 474
Control	IgG, IgG1, IgG2a, IgG2c. and IgG3 1:50	-	(M) 8.5 ± 0.8	(M) 6.6 ± 0.2	41,886 ± 6001	30 ± 3.9	64,483 ± 9998	3.4 ± 1.8	15.6 ± 3	27.7 ± 2	31.6 ± 2	21.6 ± 2	1398 ± 474
rSjAChE	IgG 1:819,200 IgG1 1:409,600 IgG2a 1:819,200 IgG2b 1:409,600 IgG2c 1:12,800 IgG3 1:6400	-	(F) 5.3 ± 1.05	(F) 9.8 ± 0.17	38,335 ± 7280	17.8 ± 2 41% ** p = 0.009	61,724 ± 12,008	9.8 ± 3.3	25 ± 3.7	34 ± 2.6	25 ± 0.9 ↓21% * p = 0.02	5.8 ± 0.8 ↓73% *** p = 0.00006	1039 ± 480 25.6% ns p = 0.77
rSjAChE		-	(M) 5.8±0.9 32% * p = 0.03	(M) 6.8 ± 0.19	38,335 ± 7280	17.8 ± 2 41% ** p = 0.009	61,724 ± 12,008	9.8 ± 3.3	25 ± 3.7	34 ± 2.6	25 ± 0.9 ↓21% * p = 0.02	5.8 ± 0.8 ↓73% *** p = 0.00006	1039 ± 480 25.6% ns p = 0.77

Note: F, female worm; M, male worm; n, the number of mice per group that survived the trial and were necropsied; ns, not significant. * = p value ≤ 0.05, ** = p value ≤ 0.001, *** = p value ≤ 0.0001.