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. 2018 Jul 29;19(8):2211. doi: 10.3390/ijms19082211

Table 1.

Changes in the levels of fetuin-A (protein or messenger RNA (mRNA)) and post-translational status of the glycoprotein during tumor progression.

Changes in the Levels of Fetuin-A (Protein or mRNA) and Post-Translational Status of the Glycoprotein During Tumor Progression Reference
Increased fetuin expression in tumor tissue (Protein) [66,67,68,69]
Increased fetuin expression in tumor tissue (Protein and mRNA) [33,53,54]
Increased fetuin-A expression in serum [70]
Increased in malignant pleural effusion of lung cancer [71]
Increased uptake of fetuin-A by tumor cells [72]
Increased high mannose glycan structures of fetuin-A in lung adenocarcinoma but not in control normal lung [73]
Increased fucosylation of fetuin-A in hepatocellular carcinoma and cholangiosarcoma [74,75]
Increased levels of fetuin-A in CSF of low grade glioma patients [76]
Reduced levels of fetuin-A in sera of patients with hematological malignancies. [64,65]
Reduced levels of fetuin-A in the microenvironment during the progression of GI tumors [50]
Reduced levels of fetuin-A in lung squamous cell carcinoma [77]