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. 2018 Aug 15;19(8):2404. doi: 10.3390/ijms19082404

Figure 1.

Figure 1

Heart function in the Langendorff preparation. Adult and aged isolated rat hearts were challenged with increasing concentrations of isoproterenol. Contractility was evaluated as developed pressure, dP/dtmax and lusitropy as dP/dtmin. Aged hearts were treated with NOX inhibitors apocynin (100 µmol/L) or VAS2870 (20 µmol/L). N = 5 hearts each group. Values are presented as mean ± standard error; n = 5. * p < 0.05, ** p < 0.01 and *** p < 0.001 vs. corresponding control.