Table 2.
Risk Factors | Classes | n | % | Without Recurrence | With Recurrence | % With Recurrence | p (Chi2) |
---|---|---|---|---|---|---|---|
Age (years) | <60 | 63 | 39.4% | 30 | 33 | 52% | 0.720 |
60–69 | 47 | 29.4% | 19 | 28 | 60% | ||
≥70 | 50 | 31.3% | 21 | 29 | 58% | ||
Smoking status | Current | 79 | 49.4% | 33 | 46 | 58% | 0.250 |
Former | 69 | 43.1% | 29 | 40 | 58% | ||
Never | 12 | 7.5% | 8 | 4 | 33% | ||
Tumor aggressiveness | Low | 41 | 25.6% | 15 | 26 | 63% | 0.284 |
High | 119 | 74.4% | 55 | 64 | 54% | ||
MPO | 0 | 154 | 96.3% | 67 | 87 | 56% | 0.753 |
1 | 6 | 3.8% | 3 | 3 | 50% | ||
SULT | 0 | 153 | 95.6% | 66 | 87 | 57% | 0.465 |
1 | 7 | 4.4% | 4 | 3 | 43% | ||
GSTM1 | 0 | 57 | 35.6% | 26 | 31 | 54% | 0.724 |
1 | 103 | 64.4% | 44 | 59 | 57% | ||
GSTP1 | 0 | 76 | 47.5% | 30 | 46 | 61% | 0.300 |
1 | 84 | 52.5% | 40 | 44 | 52% | ||
GSTT1 | 0 | 125 | 78.1% | 53 | 72 | 58% | 0.515 |
1 | 35 | 21.9% | 17 | 18 | 51% | ||
MnSOD | 0 | 106 | 66.3% | 43 | 63 | 59% | 0.255 |
1 | 54 | 33.8% | 27 | 27 | 50% | ||
COMT | 0 | 48 | 30.0% | 22 | 26 | 54% | 0.728 |
1 | 112 | 70.0% | 48 | 64 | 57% | ||
XRCC1 | 0 | 72 | 45.0% | 30 | 42 | 58% | 0.631 |
1 | 88 | 55.0% | 40 | 48 | 55% | ||
XPD | 0 | 58 | 36.3% | 23 | 35 | 60% | 0.431 |
1 | 102 | 63.8% | 47 | 55 | 54% | ||
XRCC3 | 0 | 72 | 45.0% | 29 | 43 | 60% | 0.423 |
1 | 88 | 55.0% | 41 | 47 | 53% | ||
NQO1 | 0 | 151 | 94.4% | 62 | 89 | 59% | 0.005 |
1 | 9 | 5.6% | 8 | 1 | 11% | ||
NAT1 | 0 | 110 | 68.8% | 48 | 62 | 56% | 0.966 |
1 | 50 | 31.3% | 22 | 28 | 56% | ||
NAT2 | 0 | 64 | 40.0% | 26 | 38 | 59% | 0.515 |
1 | 96 | 60.0% | 44 | 52 | 54% | ||
DNA Adducts | ≤5.6 | 123 | 76.9% | 60 | 63 | 51% | 0.019 |
>5.6 | 37 | 23.1% | 10 | 27 | 73% | ||
Exposure to PAH | Never | 100 | 62.5% | 44 | 56 | 56% | 0.934 |
Ever | 60 | 37.5% | 26 | 34 | 57% | ||
Exposure to aromatic amines | Never | 148 | 92.5% | 66 | 82 | 55% | 0.449 |
Ever | 12 | 7.5% | 4 | 8 | 67% |