Table 3.

Main characteristics of patients without/with progression and p-values of the chi-square test.

Risk Factors	Classes	Without Progression	With Progression	% With Progression	p (Chi2)
Age (years)	<60	49	14	22%	0.320
	60–69	36	11	23%
	≥70	33	17	34%
Smoking status	Current	60	19	24%	0.789
	Former	49	20	29%
	Never	9	3	25%
Tumor aggressiveness	Low	30	11	25%	0.922
	High	88	31	25%
MPO	0	115	39	25%	0.178
	1	3	3	50%
SULT	0	111	42	27%	0.106
	1	7	0	0%
GSTM1	0	39	18	32%	0.254
	1	79	24	23%
GSTP1	0	56	20	26%	0.986
	1	62	22	26%
GSTT1	0	93	32	26%	0.724
	1	25	10	29%
MnSOD	0	73	33	31%	0.049
	1	45	9	17%
COMT	0	31	17	35%	0.084
	1	87	25	22%
XRCC1	0	55	17	24%	0.493
	1	63	25	28%
XPD	0	45	13	22%	0.406
	1	73	29	28%
XRCC3	0	51	21	29%	0.448
	1	67	21	24%
NQO1	0	109	42	28%	0.065
	1	9	0	0%
NAT1	0	82	28	25%	0.734
	1	36	14	28%
NAT2	0	46	18	28%	0.660
	1	72	24	25%
DNA Adducts	≤5.6	95	28	23%	0.068
	>5.6	23	14	38%
Exposure to PAH	Never	71	29	29%	0.307
	Ever	47	13	22%
Exposure to aromatic amines	Never	109	39	26%	0.918
	Ever	9	3	25%