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. 2018 Aug 17;19(8):2436. doi: 10.3390/ijms19082436

Figure 2.

Figure 2

Figure 2

Histone acetylation state under β-adrenergic receptor (β-AR) stimulation in IWAT cell. (a) Ucp1 expression after induction by 10 µM β-AR agonist isoproterenol (iso) over time, and H3K27ac level in (b) whole cells, (c) Ucp1 enhancer region, and (d) Ucp1 proximal region after induction by 10 µM β-AR agonist isoproterenol (iso) for 4 h. IgG act as a mock control. Data are presented as mean ± S.E.M. (error bars). n = 4–6 in each group. Different letters indicate significant difference (p < 0.05) according to one-way ANOVA followed by the Tukey-Kramer multiple comparison test. Same letters indicate non-significant difference.