Table 2.

The mainstream data resources of toxicity chemicals.

Database	Database Description	Online Websites	Reference
TOXNET	A collection of toxicity databases.	https://toxnet.nlm.nih.gov/	[97]
ToxCast	High-throughput toxicity data on thousands of chemicals.	https://www.epa.gov/chemical-research/toxicity-forecaster-toxcasttm-data	[98]
Tox21	(1)Chemical Effects in Biological Systems; (2)Individual data and summaries from National Toxicology Program studies; (3)The growth, survival, pathology and other toxicology data.	https://ntp.niehs.nih.gov/results/dbsearch/index.html	[99,100]
PubChem	(1)Chemical structures; (2)Identifiers; (3)Chemical and physical properties; (4)Biological activities; (5)Toxicity data (6)Patents and health, safety and so on.	https://pubchem.ncbi.nlm.nih.gov/	[94]
DrugBank	Detailed drug data and corresponding drug target information.	https://www.drugbank.ca/	[101]
ToxBank Data Warehouse	Data for systemic toxicity.	http://www.toxbank.net/data-warehouse	[102]
ECOTOX	Single chemical environmental toxicity data on aquatic life, terrestrial plants and wildlife.	https://cfpub.epa.gov/ecotox/index.html	[103]
SuperToxic	Toxic compound data from literature and web sources.	http://bioinformatics.charite.de/supertoxic/	[104]